IGH GENE REARRANGEMENT (IGR)
: Molecular Diagnostics
: B cell gene rearrangement, IGR
: PCR and evaluated by gel electrophoresis; Laboratory Developed Test
: Lavender top (EDTA)
: Whole blood, bone marrow, paraffin embedded tissue: block, 5-10 unstained slides or 5 curls (NOTE: slides and curls 10ìm thick with accompanying before and after cut H&E slides); purified DNA (1 microgram), CSF
: Yellow top (ACDH) for whole blood or bone marrow
: 0.5 mL whole blood or bone marrow; please call Molecular Diagnostics Laboratory for other specimen type requirements
: 4 mL (whole blood, bone marrow)
: 0.5 mL whole blood or bone marrow
: EDTA and ACDH tubes: room temperature or refrigerated, purified DNA: refrigerate or freeze, paraffin block: room temperature; CSF - refrigerate
: EDTA and ACDH tubes - Room temperature: 2 days Refrigerated: 3 days; Purified DNA - indefinitely @ -70°C; Paraffin block - indefinitely; CSF - call Molecular Diagnostics Lab at 615-343-8121
Reasons for Rejection
: Decalcification (paraffin embedded tissue)Client will be notified by Molecular Diagnostics Lab if specimen is rejected.
: Once a week - variable days
: 10 days
: Detection of a clonal population of cells by PCR
: Call the Molecular Diagnostics Laboratory at 615-343-8121 if additional assistance is needed regarding specimen requirements or submission or if patient has received a transfusion in the prior 2 weeks.Click here to print the Molecular Diagnostics requisition.
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