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Vanderbilt Pathology Laboratory Services

Test Directory



CMV DETECTION BY AMPLIFIED PROBE (CMD)

Department: Molecular Infectious Disease
Test Synonym(s): CMD, CMV DNA, Cytomegalovirus by PCR
CPT Codes: 87496
Methodology: PCR (Polymerase Chain Reaction)
Reference Range: Not detected
Tube Type: CSF container - 1.0 mL, lavender top (EDTA) - 4.0 mL
Specimen: CSF or whole blood
Alternate Specimen: Need Medical Director approval
Pediatric Requirements: CSF container - 1.0 mL, lavender top (EDTA)- 1.0 mL
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Temperature: Refrigerated: 1 week; -80C: longer than 1 week
Stability: Refrigerated: 1 week; -80C: longer than 1 week
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Monday, Wednesday and Friday
Times Performed: Once per day on Monday, Wednesday and Friday (batched)
TAT: 1 - 3 days
Significance: CMV is an agent of CNS infection, primarily in immunocompromised hosts. Recognition of the presence of CMV is critical to therapy and differentiation from other potential disease etiologies. Cell culture is unreliable for recovery of CMV from CSF. PCR detection of CMV DNA in CSF is the preferred laboratory diagnostic approach to CNS disease caused by this virus.
Special Instructions:
Click here to print the Molecular Diagnostics requisition.

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