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Vanderbilt Pathology Laboratory Services

Test Directory



CMV DETECTION BY AMPLIFIED PROBE (CMD)

Department: Molecular Infectious Disease
Test Synonym(s): CMD, CMV DNA, Cytomegalovirus by PCR
CPT Codes: 87496
Methodology: PCR (Polymerase Chain Reaction)
Reference Range: Not detected
Tube Type: CSF container - 1.0 mL, lavender top (EDTA) - 4.0 mL
Specimen: CSF or whole blood
Alternate Specimen: Need Medical Director approval
Pediatric Requirements: CSF container - 1.0 mL, lavender top (EDTA)- 1.0 mL
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Temperature: Room Temperature: same day, refrigerated: overnight, frozen: longer than overnight
Stability: Room temperature: same day, refrigerated: overnight, frozen: longer than overnight
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Monday, Wednesday and Friday
Times Performed: Once per day on Monday, Wednesday and Friday (batched)
TAT: 24 hours (Monday - Friday)
Significance: This qualitative assay for cytomegalovirus (CMV) detection is majorly used for detection of CMV in cerebrospinal fluid (CSF). CMV can be an important pathogen causing encephalitis and meningitis. Recognition of the presence of CMV is critical to the therapy and differentiation. Cell cultures have not been reliable for recovering this virus from CSF. Detection of CMV DNA in CSF is now the gold standard for the laboratory diagnosis of central nervous system diseases caused by this virus.
Special Instructions: Other sources or samples may be acceptable for this test; please check with the lab, 615-936-6435.


Click here to print the Molecular Diagnostics requisition.

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