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Vanderbilt Pathology Laboratory Services

Test Directory



CMV QUANTIFICATION (CMQ)

Department: Molecular Infectious Disease
Test Synonym(s): Cytomegalovirus, CMQ, CMV DNA quant
CPT Codes: 87497
Methodology: PCR (Polymerase Chain Reaction)
Reference Range: 200 - 5,000,000 copies/mL
Tube Type: Lavender top (EDTA) - 4.0 mL
Specimen: Whole blood
Alternate Specimen: Need Medical Director approval
Pediatric Requirements: Lavender top (EDTA)- 1.0 mL
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Temperature: Room Temperature: same day, refrigerated: overnight, frozen: longer than overnight
Stability: Room temperature: same day, refrigerated: overnight, frozen: longer than overnight
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Monday - Friday
Times Performed: Batched
TAT: 24 hours (Monday - Friday)
Significance: Cytomegalovirus (CMV) is an significant pathogen in immunocompromised patients, such as organ and bone marrow transplant recipients. However, antiviral drugs must be used carefully due to side effects. As a persistent infection, it is important to differentiate between CMV infection and disease, and CMV quantitation in blood a major laboratory technique to monitor infection status and manage patients. CMV viral load by cell cultures has not been reliable and has had low sensitivity. Antigenemia assays do not measure free viruses not associated with cells and will not work with patients with low white counts. Quantification of CMV viral load by real-time PCR offers a specific, wide-range viral load with significantly shorter turn-around times.
Special Instructions: Other sources or samples may be acceptable for this test; please check with the lab, 615-936-6435.
Click here to print the Molecular Diagnostics requisition.

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