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Vanderbilt Pathology Laboratory Services

Test Directory



HERPESVIRUS-7 AMPLIFIED PROBE (H7D)

Department: Molecular Infectious Disease
Test Synonym(s): H7D, HHV7 DNA
CPT Codes: 87798
Methodology: PCR (Polymerase Chain Reaction)
Reference Range: Not detected
Tube Type: CSF container - 1.0 mL, lavender top (EDTA) - 4.0 mL
Specimen: CSF or whole blood
Alternate Specimen: Need Medical Director approval
Pediatric Requirements: CSF container - 1.0 mL, lavender top (EDTA) - 1.0 mL
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Temperature: Room Temperature: 1 week; -80C: longer than 1 week
Stability: Refrigerated: 1 week; -80C: longer than 1 week
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Sunday
Times Performed: Once per day on Sunday (batched)
TAT: 1 - 7 days
Significance: "It is estimated that the >90% of the adult population is seropositive for HHV-7. Usually, primary HHV-7 infection occurs in childhood and is associated with idiopathic fevers and/or rash illnesses. HHV-7 is responsible for a spectrum of clinical syndromes in immunocompromised patients and has been implicated as a cause of organ-specific diseases such as pneumonitis, hepatitis, encephalitis, and nonspecific febrile syndromes in transplant recipients. Convenient cell culture systems for isolation of HHV-7 from blood or CSF are not available. PCR detection of HHV-7 DNA in these specimen types is the preferred laboratory diagnostic approach to disease caused by this virus.
Special Instructions:
Click here to print the Molecular Diagnostics requisition.

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