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Vanderbilt Pathology Laboratory Services

Test Directory



HERPESVIRUS-8 AMPLIFIED PROBE (H8D)

Department: Molecular Infectious Disease
Test Synonym(s): H8D, HHV8 DNA
CPT Codes: 87798
Methodology: PCR (Polymerase Chain Reaction)
Reference Range: Not detected
Tube Type: CSF container - 1.0 mL lavender top (EDTA) - 4.0 mL
Specimen: CSF or whole blood
Alternate Specimen: Need Medical Director approval
Pediatric Requirements: CSF container - 1.0 mL, lavender top (EDTA) - 1.0 mL
Volume: 1.0 mL
Minimum Volume: 0.5 mL
Temperature: Room Temperature: 1 week; -80C: longer than 1 week
Stability: Room Temperature: 1 week; -80C: longer than 1 week
Reasons for Rejection: Alternative specimen sent without Medical Director approval
Days Performed: Sunday
Times Performed: Once per day on Sunday (batched)
TAT: 1 - 7 days
Significance: "HHV-8 is the etiologic agent for Kaposiís sarcoma and primary effusion lymphoma. This virus also displays close linkage with multicentric Castlemanís disease. HHV-8-related malignancies principally occur in immunocompromised individuals. Serologic assays for HHV-8 lack standardization, and practical systems for diagnostic isolation of HHV-8 in culture are not available. PCR detection of HHV-8 DNA offers a sensitive means of virus detection.
Special Instructions:
Click here to print the Molecular Diagnostics requisition.

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