PROTEIN C ACTIVITY (CAC)
: 50 - 120%
: Light blue top (Sodium Citrate)
: Citrated plasma - platelet poor. This sample requires double centrifugation if sending a plasma aliquot
: Peds - 2.7 mL Neonates - 1.8 mL
: 1.0 mL plasma
: 1.0 mL plasma
: Room temperature or send as a frozen plasma aliquot if sample will not be received into the lab within 4 hours.
: Room temperature: 4 hours
Reasons for Rejection
: Clotted sample, incorrectly filled tube, markedly hemolyzed sample, sample sent as whole blood > 4 hours old
: Monday - Friday
: 8:00 a.m. - 4:00 p.m.
: 1 day
: Presence of Aprotinin in the sample will result in an under estimation of the Protein C level.
: Indwelling line should be flushed with saline and 5.0 mL of blood discarded before collecting samples for coagulation assays.Tube must be full and not clotted. Deliver to lab immediately. Samples received from an outside lab must be aliqouted and frozen. Samples aliquoted for shipping must be double centrifuged prior to freezing. Grossly hemolyzed, icteric or lipemic samples may be rejected. Levels of functional protein C will be decreased in patients taking Warfarin drugs. Patients should be off anticoagulant therapy prior to measuring protein C levels.
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