Vanderbilt Medical Center - Gould Lab
   

Since 2001:

Tasto, J.J., Carnahan, R. H., McDonald, W. H., and Gould, K.L. (2001). Vectors and gene targeting modules for tandem affinity purification in Schizosaccharomyces pombe. Yeast 18:1-6.

McCollum, D., and Gould, K.L. (2001). Timing is everything: regulation of mitotic exit and cytokinesis by the MEN and SIN. Trends Cell Biol. 11:89-95.

Trautmann, S., Wolfe, B.A., Jorgensen, P., Tyers, M., Gould, K.L., and McCollum, D. (2001). Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression. Curr. Biol. 11:931-940.

Feoktistova, A., Magnelli, P., Abeijon, C., Perez, P., Lester, R.L., Dickson, R.C., and Gould, K.L. (2001). Evidence that a sphingolipase is required for fission yeast cell wall formation. Genetics 158:1397-1411

Ochotorena, I., Hirata, D., Kominani, K., Potashkin, J., Sahin, F., Wentz-Hunter, K., Gould, K.L., Sato, K., Sato, K., Yoshida, Y., Vardy, L., and Toda, T. (2001) Fission yeast Wat1/Pop3 WD-repeat protein secures genome stability through microtubule integrity and may link the splicing factor U2AF to mRNA maturation. J. Cell Sci. 114:2911-2920

Chang, L., Morrell, J.L., Feoktistova, A., and Gould, K.L. (2001) Study of cyclin proteolysis in anaphase-promoting complex (APC) mutant cells reveals the requirement for APC function in the final steps of the fission yeast septation initiation network. Mol. Cell. Biol. 21:6681-6694

Burns, C.G., Ohi, R., Mehta, S., O’Toole, I.T., Winey, M., Clark, T.A., Sugnet, C. W., Ares, Jr., M., and Gould, K.L. (2002). Removal of a single a-tubulin gene intron suppresses cell cycle arrest phenotype of splicing factor mutations in S. cerevisiae. Mol. Cell. Biol. 22:801-815

Tomlin, G., Morrell, J. L., and Gould, K.L. (2002) The spindle pole body protein, Cdc11p, links Sid4p to the fission yeast septation initiation network. Mol. Biol. Cell.13:1203-1214

Ohi, M.D., Link, A.J., Ren, L., Jennings, J.L., McDonald, W.H., and Gould, K.L. (2002) Proteomics analysis reveals stable multi-protein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol. Cell Biol.22:2011-2024

Ohi, M.D. and Gould, K.L. (2002) Characterization of interactions amongst the Cef1p-Prp19p associated splicing complex. RNA 8:798-815

MacCoss, M.J., McDonald, W.H., Saraf, A., Sadygov, R., Clark, J.M., Tasto, J.J., Gould, K.L., Wolters, D., Washburn, M., Weiss, A., Clark, J.I. and Yates, III, J.R. (2002) Shotgun identification of protein modifications from protein complexes and lens tissue. Proc. Natl. Acad. Sci. USA 99:7900-7905

Schadick, K., Fourcade, H.M., Boumenot, P., Seitz, J.J., Morrell, J.L. Chang, L., Gould, K.L., Partridge, J.F., Allshire, R.C., Kitagawa, K., Hieter, P., and Hoffman, C.S. (2002) Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgt1p family, is required for glucose/cAMP signaling, cell wall integrity, and septation. Eukaryotic Cell 1:558-567

Morrell, J.L., and Gould, K.L. (2002) Regulating the end of the cell cycle: functions of the MEN and SIN in yeast. Recent Res. Devel. Mol. Cell. Biol. 13:13-32

Yoon, H.-J., Feoktistova, A., Wolfe, B. A., Jennings, J.L., Link, A.J., and Gould, K.L. (2002) Proteomics analysis identifies new components of the fission and budding yeast anaphase promoting complexes. Curr. Biol. 12:2048-2054

Guertin, D.A., Venkatram, S., Gould, K.L., and McCollum, D. (2002) Dma1 prevents mitotic exit and cytokinesis by inhibiting the Septation Initiation Network (SIN). Dev. Cell 3:779-790

Gould, K.L. (2003) Protein kinases driving the cell cycle. In “Molecular Biology of Schizosaccharomyces pombe” Egel, R. (ed)., Springer-Verlag, Heidelberg, Germany.

Ohi, M.D., Vanderkooi, C.W., Rosenberg, J.A., Chazin, W. J., and Gould, K.L. (2003) Structural insights into the U-box, a domain associated with multi-ubiquitination. Nat. Struct. Biol. 10:250-255

Tasto, J.J., Morrell, J.L., and Gould, K.L. (2003) An anillin homolog, Mid2p, acts during fission yeast cytokinesis to organize the septin ring and promote cell separation. J. Cell Biol. 160:1093-1103

Zhang, Y.-Z., Cheng, H., Gould, K.L., Golemis, E.A., and Roder, H. (2003) Structure, stability and function of hDim1 investigated by NMR, circular dichroism and mutational analysis. Biochemistry 42:9609-9618

Carnahan, R.H. and Gould, K.L. (2003) The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosacchromyces pombe. J. Cell Biol. 162:851-62

Morrell, J.L., Tomlin, G.C., Rajagopalan, S., Venkatram, S., Feoktistova, A.S., Tasto, J.J., Mehta, S., Jennings, J.L., Link, A., Balasubramanian, M.K., and Gould, K.L. (2004) Sid4p-Cdc11p assembles the septation initiation network and its regulators at the S. pombe SPB. Curr. Biol. 14:579-84

Venkatram, S., Tasto, J.J., Feoktistova, A., Jennings, J.L., Link, A., and Gould, K.L. (2004) Identification and characterization of two novel proteins affecting fission yeast {gamma}-tubulin complex function. Mol. Biol. Cell 15:2287-2301

Wolfe, B.A. and Gould, K.L. (2004) Fission yeast Clp1p phosphatase affects G(2)/M transition and miotic exit through Cdc25p inactivation. EMBO J. 23:919-29

Wolfe, B.A. and Gould, K.L. (2004) Inactivating Cdc25, mitotic style. Cell Cycle 3:601-603

Gould, K.L. (2004) Protocols for experimentation with Schizosaccharomyces pombe. Editorial. Methods 33:187-188

Gould, K.L., Ren, L., Feoktistova, A.S., Jennings, J.L., and Link, A.J. (2004). Tandem affinity purification and identification of protein complex components. Methods 33:239-244

Morrell, J.L., Breeding, C.S. and Gould, K.L. (2004) The GIN4 family kinase, Cdr2p, functions independently of septins in fission yeast. J. Cell Science 117:5293-5302

An, H., Morrell, J.L., Tasto, J.J., Jennings, J.L. Link, A.J., and Gould, K.L. (2004) Requirements of S. pombe septins for complex formation, localization and function. Mol. Biol. Cell 15:5551-5564

Ohi, M.D., Vanderkooi, C.W., Rosenberg, J.A., Ren, L., Hirsch, J. P., Chazin, W. J., and Walz., T. and Gould, K.L. (2005) Structural and functional analysis of the essential pre-mRNA splicing factor Prp19p. Mol. Cell. Biol. 25:451-460

Alonso-Nuñez, M. L., An, H., Mehta, S., Petit, C., Sipiczki, M., del Rey, F., Gould, K.L., and Vázquez de Aldana, C.R. (2005) Ace2p controls the expression of genes required for cell separation in Schizosaccharomyces pombe. Mol. Biol. Cell. 16:2003-2017

Wolfe, B.A. and Gould, K.L. (2005) Split decisions: coordinating cytokinesis in yeast. Trends Cell Biol. 15:10-18

Ren, L., Feoktistova, A., McDonald, W.H., Den Haese, G., Morrell, J.L., Gould, K.L. (2005) Analysis of the role of phosphorylation in fission yeast Cdc13/cyclin B function. J. Biol. Chem. 280:14591-14596

Carnahan, R.H., Feoktistova, A., Ren, L., Niessen, S., Yates, J.R., Gould, K.L. (2005) Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Eukaryot. Cell 4:577-587

Morrell-Falvey, J.L., Ren, L., Feoktistova, A., Haese, G.D., Gould, K.L. (2005) Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p. J. Cell Sci.118:5563-5573

Petit, C.S., Mehta, S., Roberts, R.H., Gould, K.L. (2005) Ace2p contributes to fission yeast septin ring assembly by regulating mid2+ expression. J. Cell. Sci. 118(Pt 24):5731-5742

Venkatram, S., Jennings , J.L., Link, A., Gould, K.L. (2005) Mto2p, a novel fission yeast protein required for cytoplasmic microtubule organization and anchoring of the cytokinetic actin ring. Mol. Biol. Cell 16:3052-63

Martin-Cuadrado, A.B., Morrell, J.L., Konomi, M., An, H., Petit, C., Osumi, M., Balasubramanian, M., Gould, K.L., del Rey, F., and Vazquez de Aldana, C.R. (2005) Role of septins and exocyst complex in the function of hydrolytic enzymes responsible for fission yeast cell separation. Mol. Biol. Cell 16:4867-4881

Vander Kooi, C.W., Ohi, M.D., Rosenberg, J.A., Oldham, M.L., Newcomer, M.E., Gould, K.L., Chazin, W.J. (2006) The Prp19 U-box Crystal Structure Suggests a Common Dimeric Architecture for a Class of Oligomeric E3 Ubiquitin Ligases. Biochemistry 45(1):121-130

Mehta, S. and Gould, K.L. (2006) Identification of functional domains within the SIN kinase Cdc7. J. Biol. Chem. 281(15):9935-41

Rosenberg, J.A., Tomlin, G.C., McDonald, W.H., Snydsman, B.E., Muller, E.G., Yates, J.R. 3rd, Gould, K.L. (2006) Ppc89 Links Multiple Proteins, Including the Septation Initiation Network, to the Core of the Fission Yeast Spindle-Pole Body. Mol. Biol.Cell 17(9):3793-805

Wolfe, B.A., McDonald, W.H., Yates, Jr., J. R., and Gould, K.L. (2006) Phosphorylation-dependent regulation of the Cdc14/Clp1 phosphatase delays mitotic events in S. pombe. Dev.Cell 11:423-430

Yoon, H.-J., Feoktistova, A., Wolfe, B. A., Jennings, J.L., Link, A.J., and Gould, K.L. (2006) Role of Hcn1 and its phosphorylation in fission yeast APC/C function. J. Biol. Chem. 281(43):32284-93

Ohi, M.D., Ren, L., Wall, J.S., Gould, K.L., and Walz, T. (2007) Structural characterization of the fission yeast U5U2/U6 spliceosome complex. PNAS USA 104(9): 3195-3200

Clifford, DM, Chen, CT, Roberts, RH, Feoktistova, A, Wolfe, BA, Chen, JS, McCollum, D, Gould, KL. (2008) The role of Cdc14 phosphatases in the control of cell division. Biochem. Soc. Trans. 36(Pt 3): 436-8

Clifford, DM, Wolfe, BA, Roberts-Galbraith, RH, McDonald, WH, Yates, JR, Gould, KL. (2008) The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1. J Cell Biol. 181(1): 79-88


(updated 8/7/08)

   
   

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