Publications

2013
Miraldi, ER, Sharfi, H, Friedline, RH, Johnson, H, Zhang, T, Lau, KS, Ko, HJ, Curran, TG, Haigis, KM, Yaffe, MB, Bonneau, R, Lauffenburger, DA, Kahn, BB, Kim, JK, Neel, BG, Saghatelian, A, White, FM. 2013. Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice. Integrative Biology 5(7): 940-963.
2012
Lau, KS, Cortez-Retamozo, V, Philips, SR, Pittet, MJ, Lauffenburger, DA, Haigis, KM. 2012. Multi-scale in vivo systems analysis reveals the influence of immune cells on TNF-a-induced apoptosis in the intestinal epithelium. PLoS Biology 10(9):e1001393.
Lau, KS, Zhang, T, Kendall, KR, Lauffenburger, D, Gray, NS, Haigis, KM. 2012. BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. PLoS One 7(7):e41343.
2011
Lau, KS, Juchheim, AM, Cavaliere, KR, Philips, SR, Lauffenburger, DA, Haigis, KM. 2011. In vivo systems analysis identifies spatial and temporal aspects of the modulation of TNF-a-induced apoptosis and proliferation by MAPKs. Science Signaling 4(165):ra16.
Mkhikian, H, Grigorian, A, Li, CF, Chen, HL, Newton, B, Zhou, RW, Beeton, C, Torossian, S, Tatarian, GG, Lee, SU, Lau, K, Walker, E, Siminovitch, KA, Chandy, KG, Yu, Z, Dennis, JW, Demetriou, M. 2011. Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis. Nature Communications 2: 334.
2009
Lau, KS, Haigis, KM. 2009. Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer. Molecule and Cells 28(4):315-320.
Dennis, JW, Lau, KS, Demetriou, M, Nabi, IR. 2009. Adaptive regulation at the cell surface by N-glycosylation. Traffic 10(11):1569-1578.
2008
Beheshti Zavareh, R, Lau, KS, Hurren, R, Datti, A, Ashline, DJ, Gronda, M, Cheung, P, Simpson, CD, Liu, W, Wasylishen, AR, Boutros, PC, Shi, H, Vengopal, A, Jurisica, I, Penn, LZ, Reinhold, VN, Ezzat, S, Wrana, J, Rose, DR, Schachter, H, Dennis, JW, Schimmer, AD. 2008. Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Research 68(16): 6688-6697.
Katz, D, Ito, E, Lau, KS, Mocanu, JD, Bastianutto, C, Schimmer, AD, Liu, FF. 2008. Increased efficiency for performing colony formation assays in 96-well plates: novel applications to combination therapies and high-throughput screening. Biotechniques 44(2):ix-xiv.
Lau, KS, Dennis, JW. 2008. N-Glycans in cancer progression. Glycobiology 18(10): 750-760.
Lau, KS, Khan, S, Dennis, JW. 2008. Genome-scale identification of UDP-GlcNAc-dependent pathways. Proteomics 8(16):3294-3302.
2007
Lau, KS, Partridge, EA, Grigorian, A, Silvescu, CI, Reinhold, VN, Demetriou, M, Dennis, JW. 2007. Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell 129(1): 123-134.
Mendelsohn, R, Cheung, P, Berger, L, Partridge, E, Lau, K, Datti, A, Pawling, J, Dennis, JW. 2007. Complex N-glycan and metabolic control in tumor cells. Cancer Research 67(20): 9771-9780.
2003
Cheung, J, Estivill, X, Khaja, R, MacDonald, JR, Lau, K, Tsui, LC, Scherer, SW. 2003. Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence. Genome Biology 4(4): R25.
2002
Lau, KS, Mantas, M, Chass, GA, Ferretti, FH, Estrada M, Zamarbide G, Csizmadia, IG. 2002. Ab initio and DFT conformational analysis of selected flavones: 5,7-dihydroxyflavone (chrysin) and 7,8-dihydroxyflavone. Canadian Journal of Chemistry 80(7): 845-855.