VUMC Main Calendar Events
Cardiothoracic Anesthesiology Conference: Ash Shah
6:10 am - 7:00 am
Topic: ACS Management- A Surgeon's Perspective
Presenter: Dr. Ash Shah
Location: MCE-NT 5053
Contact: Lindsey Kilgore
6:30 am - 7:00 am
Topic: "Oral Boards - #5"
Presenter: Dr. James Blair
Location: 3161 MCE
Reading: Chapters 1, 2, 5, & 10
Contact: Misty White
Maternal Physiologic Changes & Neuraxial Anesthesia
7:00 am - 8:15 am
Topic: "Maternal Physiologic Changes & Anesthetic Implications"
Presenter: Dr. Tessa McClung
Location: 4203 VUH
Reading: Chapter 2
Contact: Le'Rae Stanton
Infection, Inflammation, & Immunity Frontiers
11:00 am - 12:00 pm
Long-range Transcriptional Architecture of the IL2 Gene - Implications for Autoimmune Disease Susceptibility
Andrew D. Wells, Ph.D.
Associate Professor of Pathology and Laboratory Medicine
Program Leader, Transplant Immunobiology, Institute for Immunology
Perelman School of Medicine at the University of Pennsylvania
Co-Director, Center for Spatial and Functional Genomics
The Children’s Hospital of Philadelphia
Vanderbilt Centers for Immunobiology, Microbial Pathogenesis, Vanderbilt Vaccine Center, Medicine Divisions of Rheumatology, Pediatric Infectious Diseases, and Infectious Diseases
Contact: Eve Stephens
Flexner Dean's Lecture
12:00 pm - 1:00 pm
Dr. Eric Horvitz
Co-Sponsored - Biomedical Informatics invitation
Epidemiology Grand Rounds
12:00 pm - 1:00 pm
“Interventions for Increasing HPV Vaccination for Cancer Prevention” by Pam Hull, PhD,
Assistant Professor, Division of Epidemiology, VUMC
Contact: Jan Cao
Strong Inside Book Signing and Meet/Greet
12:00 pm - 1:00 pm
Please join us as we welcome Perry Wallace, Godfrey Dillard and Strong Inside author, Andrew Maraniss for an informal meet, greet and book signing. Lunch served.
Contact: Jeff S. King
Biophotonics Center Seminar 9/27 at 12 pm - Dr. Eric P. Skaar
12:00 pm - 1:15 pm
When: Tuesday, September 27, 2016, from 12:00 noon – 1.15 PM (Lunch will be served)
Where: Stevenson Center (SC) 5326
Title:â€‹ Exploiting heme toxicity to generate light-based treatments for infectious diseases
Presenter: â€‹Dr. Eric P. Skaar, PhD, MPH, Ernest W. Goodpasture Professor of Pathology, Vanderbilt University
Abstract: Gram-positive bacteria cause the majority of skin and soft tissue infections (SSTIs), resulting in the most common reason for clinic visits in the United States. Recently it was discovered that Gram-positive pathogens utilize a unique heme biosynthesis pathway, which implicates this pathway as a novel target for development of antibacterial therapies. In this talk I will discuss the identification of a small molecule activator of coproporphyrinogen oxidase (HemY) from Gram-positive bacteria, an enzyme essential for heme biosynthesis. Activation of HemY induces accumulation of coproporphyrin III and leads to photosensitization of Gram-positive pathogens. In combination with light, HemY activation reduces bacterial burden and tissue ulceration in murine models of SSTI. Thus, small molecule activation of HemY represents an effective strategy for the development of light-based antimicrobial therapies.
Bio: Dr. Eric earned his B.S. in Bacteriology from the University of Wisconsin at Madison, his Ph.D. in Immunology and Microbial Pathogenesis from Northwestern University, and his M.P.H. in Epidemiology and Biostatistics from Northwestern University. His research team focuses on identifying factors and processes involved in the battle for metal between bacterial pathogens and their hosts. His group lays a special emphasis on studying the interactions between vertebrate hosts and the bacterial pathogens such as Staphylococcus aureus (most common cause of skin and soft tissue infections), Bacillus anthracis (causative agent of anthrax), Acinetobacter baumannii (emerging cause of pneumonia and wound infections) and Clostridium difficile (major cause of antibiotic-associated diarrhea).
Pedro Manuel Garcia - Dissertation Defense
1:00 pm - 4:00 pm
"Total Synthesis of Gombamide A and Actinophenanthroline A. Discovery, Optimization and Characterization of Novel Positive Allosteric Modulators for the Matabotropic Glutamate Receptor Subtype 1"
Pedro Manuel Garcia, Chemical and Physical Biology (Professor Gary A. Sulikowski, Chair of the Ph.D. Committee)
Contact: Graduate School
AP Professional Development/Grand Rounds Committee
2:00 pm - 3:00 pm
Meeting for the Advanced Pratice Professional Development/Grand Rounds Committee
Time: 2-3 p.m.
Location: Light Hall 439
Contact: Kathleen Sweeney
Otolaryngology/ENT Interest Group Intro Meeting
5:00 pm - 7:00 pm
The Otolaryngology/ENT Interest Group will be having its first meeting of the year! We will be having a meet and greet with faculty and residents from the Department of Otolaryngology. Please join us if you are interested in pursing a career in otolarynology or would like to learn more about the field! Dinner will be provided.