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Phosphoenolpyruvate carboxykinase (PEPCK)-Cre - Renal specific transgenic database

Common name Phosphoenolpyruvate carboxykinase (PEPCK)-Cre
Mouse strain Other
Genebank listing: PCK1 (32767)
Source Volker Haase (email)
Renal cell types Proximal tubule S1 segment,Proximal tubule S2 segment,Proximal tubule S3 segment,Proximal tubule
Extent of expression/recombination in renal target cells Expressed in renal cortex and outer medulla. Expressed in most S1 and S2 and all S3 segments of the proximal tubule.
Other cell types Some periportal hepatocytes
Applications
Image (click to zoom) None provided
References
  • Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, Saito Y, Johnson RS, Kretzler M, Cohen CD, Eckardt KU, Iwano M, Haase VH. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest (2007) 117:3810-20 View in PubMed

  • Rankin EB, Tomaszewski JE, Haase VH. Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor. Cancer Res (2006) 66:2576-83 View in PubMed

Availability Unknown
Added on/by 2010-01-20 / Donald Kohan
Modified on/by 2010-03-01 / Donald Kohan