Clinical Research

The Perioperative Clinical Research Institute provides a full range of services necessary for successful clinical research. These services include regulatory management, data management, contracts management, biostatistics, bioinformatics, and financial oversight.

Improving healthcare through clinical research and education is our primary goal. Our research includes both industry-sponsored and investigator-initiated clinical projects and focuses on the advancement of medical practice in the fields of perioperative care, chronic pain and medical devices. Our investigators are practicing physicians who use their clinical expertise to develop research protocols that seek to answer clinically-significant questions.

Current studies focus on a wide variety of clinical issues including the use of wireless vital sign monitors for early detection of adverse events on post-surgical floors, the effects of anesthesia on the developing brain of a child, post-operative pain, nausea, vomiting, inflammation, obstructive sleep apnea and delirium. Newer projects include:

  • Testing the utility and accuracy of software designed to automate gathering of patient medication lists and development of medical problem lists over the web;

  • Founding membership in the Multicenter Perioperative Outcomes Group (MPOG), a large registry of anesthetic cases contributed, along with functional data definitions, by hospitals with electronic anesthesia information management systems, all with the goal of facilitating large data-set research in anesthesia outcomes.

The PCRI is overseeing more than 40 active clinical trials, with many more studies now in the process of approval. PCRI is directed by Dr. Edward Sherwood and Director of Clinical Trials Research Damon Michaels. The team consists of highly-trained and broadly-experienced research professionals, including three research nurse specialists, two research assistants and one clinical trials associate.


This page was last updated April 10, 2013 and is maintained by