Welcome to the website for the laboratory of Dr. Angela Jefferson. Our research focuses on discovering underlying mechanisms for unhealthy cognitive changes in older adults, such as mild cognitive impairment, for the purpose of informing prevention and therapeutic targets.
Mild cognitive impairment is characterized by mild memory and cognitive changes among older adults. Scientists believe mild cognitive impairment is a very early stage of Alzheimer’s disease. Alzheimer’s disease is a major public health issue and affects over 5 million Americans.
If the scientific community is unable to find an effective prevention or treatment approach soon, the number of individuals over age 65 who are affected by Alzheimer’s disease may exceed 13 million by 2050. Therefore, research to advance prevention, diagnosis, and treatment of mild cognitive impairment and Alzheimer’s disease is critically important to minimize this growing public health burden.