MSRC Mass Spectrometry Research and Development

MSRC R&D Lab Publications

The most recent articles are at the top of this page. We currently have all articles from the present day back to January 2005. For Quicker Access, Please Select a Year, or scroll down this page.

2005  2006  2007

2007 Articles

  • Caldwell RL, Opalenik SR, Davidson JM, Caprioli RM, Nanney LB. Tissue profiling MALDI mass spectrometry reveals prominent calcium-binding proteins in the proteome of regenerative MRL mouse wounds.Wound Repair Regen. 2007 Dec 13.
  • Sinha TK, Khatib-Shahidi S, Yankeelov TE, Mapara K, Ehtesham M, Cornett DS, Dawant BM, Caprioli RM, Gore JC. Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging. Nat Methods. 2007 Dec 16.
  • Herring KD, Oppenheimer SR, Caprioli RM. Direct tissue analysis by matrix-assisted laser desorption ionization mass spectrometry: application to kidney biology. Semin Nephrol. 2007 Nov;27(6):597-608.
  • Chaurand P, Rahman MA, Hunt T, Mobley JA, Gu G, Latham JC, Caprioli RM, Kasper S. Monitoring mouse prostate development by profiling and imaging mass spectrometry.Mol Cell Proteomics. 2007 Nov 8.
  • Yildiz PB, Shyr Y, Rahman JS, Wardwell NR, Zimmerman LJ, Shakhtour B, Gray WH, Chen S, Li M, Roder H, Liebler DC, Bigbee WL, Siegfried JM, Weissfeld JL, Gonzalez AL, Ninan M, Johnson DH, Carbone DP, Caprioli RM, Massion PP. Diagnostic accuracy of MALDI mass spectrometric analysis of unfractionated serum in lung cancer.J Thorac Oncol. 2007 Oct;2(10):893-901.
  • Cornett DS, Reyzer ML, Chaurand P, Caprioli RM. MALDI imaging mass spectrometry: molecular snapshots of biochemical systems.Nat Methods. 2007 Oct;4(10):828-33. Review.
  • Nilsson A, Sköld K, Sjögren B, Svensson M, Pierson J, Zhang X, Caprioli RM, Buijs J, Persson B, Svenningsson P, Andrén PE. Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins.J Proteome Res. 2007 Oct;6(10):3952-61. Epub 2007 Sep 18.
  • McLean, J.A., Ridenour, W.B., Caprioli, R.M.  Profiling and imaging of tissues by imaging ion mobility-mass spectrometry.  J Mass Spectrom 42(8): 1099-105, 2007
  • Suzuki, K., Yu, X., Chaurand, P., Araki, Y., Lareyre, J.J., Caprioli, R.M., Orgebin-Crist, M.C., Matusik, R.J.  Epididymis-specific lipocalin promoters. Asian J Androl 9(4): 515-21, 2007.
  • Raj J.U., Aliferis, C., Caprioli, R.M., Cowley, A.W. Jr., Davies, P.F., Duncan, M.W., Erle, D.J., Erzurmum, S.C., Finn, P.W., Ischiropoulos, H., Kaminski, N.,  Kleeberger, S.R., Leikauf,  G.D., Loyd, J.E., Martin, T.R., Matalon, S., Moore, J.H., Quackenbush, J., Sabo-Atwood, T., Shapiro, S.D., Schnitzer, J.E., Schwartz, D.A., Schwiebert, L.M., Sheppard, D., Ware, L.B., Weiss, S.T., Whitsett, J.A., Wurfel, M.M., Matthay, M.A.   Genomics and proteomics of lung disease: conference summary.  Am J Physiol Lung Cell Mol Physiol 293(1): L45-51, 2007.
  • Norris J.L., Cornett D.S., Mobley J.A., Andersson M., Seeley E.H., Chaurand P., Caprioli R.M.  Processing MALDI mass spectra to improve mass spectral direct tissue analysis.  Int J Mass Spectrom 260(2-3):212-221, 2007.
  • Taguchi F, Solomon B, Gregorc V, Roder H, Gray R, Kasahara K, Nishio M, Brahmer J, Spreafico A, Ludovini V, Massion PP, Dziadziuszko R, Schiller J, Grigorieva J, Tsypin M, Hunsucker SW, Caprioli R, Duncan MW, Hirsch FR, Bunn PA Jr, Carbone DP.  Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors:  a multicohort cross-institutional study.  J Natl Cancer Inst. 99:11,838-46, 2007.
  • Chaurand, P., Schriver, K.E., Caprioli, R.M.  Instrument design and characterization for high resolution MALDI-MS imaging of tissue sections.  J Mass Spectrom  42(4):476-89, 2007. 
  • Hamblin, M., Friedman, D.B., Hill, S., Caprioli, R.M., Smith, H.M., Hill, M.F.    Alterations in the diabetic myocardial proteome coupled with increased myocardial oxidative stress underlies diabetic cardiomyopathy.  J. Mol Cell Cardiol 42(4): 884-95, 2007.
  • Groseclose, M.R., Andersson, M., Hardesty, W.M., Caprioli, R.M.  Identification of proteins directly from tissue:  in situ tryptic digestions coupled with imaging mass spectrometry.  J Mass Spectrom 42(2):  254-262, 2007.
  • M’koma, A.E., Blum, D.L., Norris, J.L., Koyama, T, Billheimer. D., Motley S, Ghiassi M., Ferdowsi, N., Bhowmick, I., Chang, S.S., Fowke, J.H., Caprioli, R.M., Bhowmick, N.A.  Detection of pre-neoplastic and neoplastic prostate disease by MALDI profiling of urine.  Biochem Biophys Res Commun. 353(3): 829-34, 2007
  • Reyzer, M.L., Caprioli, R.M.  MALDI-MS based imaging of small molecules and proteins in tissues.  Curr Opin Chem Biol.  11(1): 29-35, 2007.

2006 Articles

  • Massion P.P., Caprioli RM.  Proteomic strategies for the characterization and the early detection of lung cancer.  J Thorac Oncol. 1(9): 1027-39, 2006.
  • Chaurand, P., Norris, J.L., Cornett, D.S., Mobley, J.A., Caprioli, R.M.  New Developments in Profiling and Imaging of Proteins from Tissue Sections by MALDI Mass Spectrometry.  J Proteome Res.  5(11): 2889-2900, 2006.
  • Friedman, D.B., Wang, S.E, Whitwell, C.W., Caprioli, R.M, Arteaga, C.L.  Multi-variable Difference Gel Electrophoresis and Mass Spectrometry:  A case Study on TGF-beta and ErbB2 signaling.  Mol Cell Proteomics Oct 5, 2006 [Epub ahead of print].
  • Khatib-Shahidi, S., Andersson, M., Herman, J.L., Gillespie, T.A., Caprioli, R.M.  Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry.  Anal Chem. 78(18):6448-56, 2006.
  • Johnson, M.D., Floyd, J.L., Caprioli, R.M.  Proteomics in diagnostic neuropathology. J Neuropathol Exp Neurol. 65(9):837-45, 2006.
  • Amann, J.M., Chaurand, P., Gonzalez, A., Mobley, J.A., Massion, P.P., Carbone, D.P., Caprioli, R.M.  Selective profiling of proteins in lung cancer cells from fine-needle aspirates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.  Clin Cancer Res. 12(17):5142-50, 2006.
  • Cornett, D.S., Mobley, J.A., Dias, E.C., Andersson, M., Arteaga, C.L., Sanders, M.E., Caprioli, R.M.  A novel histology directed strategy for MALDI-MS tissue profiling that improves throughput and cellular specificity in human breast cancer.  Mol Cell Proteomics.  5(10):1975-83, 2006.
  • Chaurand, P., Cornett, D.S., Caprioli, R.M.  Molecular imaging of thin mammalian tissue sections by mass spectrometry.  Curr Opin Biotechnol. 17(4):431-6, 2006.
  • Meistermann, H., Norris, J.L., Aerni, H.R., Cornett, D.S., Freidlein, A., Erskine, A.R., Augustin, A., De Vera Murdry, M.C., Ruepp, S., Suter, L., Langen, H., Caprioli, R.M., Ducret, A.   Biomarker discovery by imaging mass spectrometry: Transthyretin is a biomarker for gentamicin-induced nephrotoxicity in rat.  Mol Cell Proteomics.  5(10):1876-1886, 2006.
  • Luka, Z., Ham, A.J., Norris, J.L., Yeo, E.J., Yermalitsky, V., Glenn, B., Caprioli, R.M., Liebler, D.C., Wagner, C.  Identification of phosphorylation sites in glycine N-methyltransferase from rat liver.   Protein Sci.  15(4):785-94, 2006.
  • Skold K., Svensson M., Nilsson A., Zhang, X., Nydahl K., Caprioli, R.M., Svenningsson P., Andren, P.E.  Decreased striatal levels of PEP-19 following MPTP lesion in the mouse.  J Proteome Res.  5(2): 262-9, 2006.
  • Aerni, H-R., Cornett, D.S., Caprioli, R.M.  Automated Acoustic Matrix Deposition for MALDI Sample Preparation.  Anal Chem 78(3): 827-834, 2006.
  • Suzuki, K., Yu, X., Chaurand, P., Araki, Y., Lareyre, J.J., Caprioli, R.M.  Epididymis-specific promoter-driven gene targeting: A transcription factor which regulates epididymis-specific gene expression. Mol Cell Endocrinol.  250(1-2):184-9, 2006.

2005 Articles

  • Xie, L., Xu, B.J., Gorska, A.E., Shyr, Y., Schwartz, S.A., Cheng, N., Levy, S., Bierie, B., Caprioli, R.M., Moses, H.L.  Genomic and proteomic analysis of mammary tumors arising in transgenic mice.  J Proteome Res.  4(6): 2088-98, 2005.
  • Caldwell, R.L., Holt, G.E., Caprioli, R.M.  Tissue Profiling by MALDI Mass Spectrometry Distinguishes Clinical Grades of Soft Tissue Sarcomas.  Cancer Genomics & Proteomics 2:333-346, 2005.
  • Caprioli, R.M.  Deciphering protein molecular signatures in cancer tissues to aid in diagnosis, prognosis, and therapy.  Cancer Res. 65(23):10642-5, 2005.
  • Wiseman J.M., Puolitaival, S.M., Takats, Z., Cooks, R.G., Caprioli, R.M.  Mass spectrometric profiling of intact biological tissue by using desorption electrospray ionization.  Agnew Chem Int Ed Engl. 44(43): 7094-7, 2005.
  • Norris, J.L., Hangauer, M.J, Porter, N.A., Caprioli, R.M.  Nonacid cleavable detergents applied to MALDI mass spectrometry profiling of whole cells. J Mass Spectrom 40(10):1319-1326, 2005.
  • Zimmerman, L.J., Wernke, G.R., Caprioli, R.M., Liebler, D.C.  Identification of Protein Fragments as Pattern Features in MALDI-MS Analyses of Serum.  J Proteome Res. 4(5):1672-80, 2005.
  • Jamshedur Rahman, S.M., Shyr, Y., Yildiz, P.B., Gonzalez, A.L., Li H., Zhang, X., Chaurand P., Yanagisawa, K., Slovis, B.S., Miller, R.F., Ninan, M., Miller, Y.E., Franklin W.A., Caprioli, R.M., Carbone D.P., Massion P.P.  Proteomic Patterns of Preinvasive Bronchial Lesions.  Am J Respir Crit Care Med. 10;22, 2005.
  • Schwartz, S.A., Weil, R.J., Thompson, R.C., Shyr, Y., Moore, J.H., Toms, S.A., Johnson, M.D., Caprioli, R.M.  Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry.  Cancer Res 65(17):7674-81, 2005
  • Hu X, Friedman D, Hill S, Caprioli R, Nicholson W, Powers AC, Hunter L, Limbird LE.  Proteomic exploration of pancreatic islets in mice null for the {alpha} 2A adrenergic receptor.  J Mol Endocrinol. 35(1): 73-88, 2005.
  • Reyzer ML, Caprioli RM.  MALDI Mass Spectrometry for Direct Tissue Analysis:  A New Tool for Biomarker Discovery.  J Proteome Res 4(4): 1138-42, 2005.
  • Aebersold R, Anderson L, Caprioli R, Druker B, Hartwell L, Smith R.  Perspective:  a program to improve protein biomarker discovery for cancer.  J Proteome Res. 4(4): 1104-1109, 2005.
  • Xu BJ, Shyr Y, Liang X, Ma, LJ, Donnert EM, Roberts JD, Zhang X, Kon V, Brown, NJ, Caprioli RM, Fogo AB.  Proteomic Patterns and Prediction of Glomerulosclerosis and its Mechanisms.  J Am Soc Nephrol.  16: 2967-2975, 2005.
  • Norris JL, Porter NA, Caprioli RM.  Combination Detergent/MALDI Matrix:  Functional Cleavable Detergents for Mass Spectrometry.  Anal Chem 77(15): 5036-40, 2005.
  • Laurent C, Levinson DF, Schwartz SA, Harrington PB, Markey SP, Caprioli RM, Levitt P.  Direct profiling of the cerebellum by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry:  A methodological study in postnatal and adult mouse.  J Neurosci Res.  81(5): 613-21, 2005.
  • Gao N, Ishii K, Mirosevich J, Kuwajima S, Oppenheimer SR, Roberts RL, Jiang M, Yu X, Shappell SB, Caprioli RM, Stoffel M, Hayward SW, Matusik RJ.  Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.  Development 132(15): 3431-43, 2005.
  • Crecelius AC, Cornett DS, Caprioli RM, Williams B, Dawant BM, Bodenheimer B.  Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry.  J Am Soc Mass Spectrom 16(7): 1093-99, 2005.
  • Pierson J, Svenningsson P, Caprioli RM, Andren PE.  Increased levels of ubiquitin in the 6-OHDA-lesioned striatum of rats.  J Proteome Res 4(2): 223-226, 2005.
  • Ma, S, Hill, K.E., Burke, R.F., Caprioli, R.M.  Mass Spectrometric determination of selenenyllsulfide linkages in rat selenoprotein P.  J Mass Spectrom. 40(3): 400-404, 2005.
  • Caldwell, R.L, Caprioli, R.M.  Tissue profiling by mass spectrometry:  A review of methodology and applications. Mol Cell Proteomics. 4(4): 394-401, 2005.
  • Chaurand, P, Schwartz, S.A., Reyzer, M.L., Caprioli R.M.  Imaging Mass Spectrometry: Principles and Potentials. Toxicol Path. 33: 92-101, 2005.


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