Department of Pathology, Microbiology, and Immunology



   Joyce E. Johnson, M.D.j



Dept of Pathology, Microbiology and Immunology
Director, Anatomic Pathology, VA Medical Center




   Contact Information


Office Location:

C-2301B MCN

Phone: 615-322-2095


Campus Mail address:

Pathology, Microbiology and Immunology-3rd Fl

C-3321 MCN (2561)


US Mailing address:

Vanderbilt University School of Medicine

Pathology, Microbiology and Immunology-3rd Fl

C-3321 MCN

Nashville, TN 37232-2561


Fax: 615-322-0511

E-mail:  joyce.johnson@vanderbilt.edu






M.D., Vanderbilt
B.A., Rice



Research Keywords



Respiratory Syncytial Virus, Pediatric Pneumonia, Cytopathology, Cervical Neoplasia, interstitial lung disease, pediatric lung disease, lung transplantation, lung cancer



Research Description



. . .



Clinical Research Description



My primary interest is in the histopathology and immunopathology of pediatric viral pneumonias. I am also working on the etiology and pathogenesis of idiopathic interstitial lung diseases. In addition, I have an ongoing interest in the cytologic diagnosis of disease.






King MS, Eisenberg RE, , Newman JH, Tolle J, Harrell NH, Ninan M, Lambright ES, Sheller JR, , Johnson JE, Miller RF. . Exercise dysfunction associated with constrictive bronchiolitis in United States soldiers returning from Iraq and Afghanistan. . NEJM, 365, 222-230, 2011

Lopez MF, Monsalvo AC, Batalle JP, Zea J, Maskin B, Bugna J, Krause J, Rubinstein C, Aguilar L, Dalurzo L, Libster R, Savy V, Baumeister E, Aguilar L, Cabral G, Font J, Weller K, Echavarria M, Edwards KM, Chappell JD, Williams JV, Crowe JE, Johnson J, Melendi GA, Polack FP. . Severe pandemic 2009 H1N1 Influenza disease due to pathogenic immune complexes. . Nature Medicine, 17, 195-199, 2011

Crossno, PF, Polosukhin, VV, Blackwell, TS, Johnson, JE, Markin, C, Moore, PE, Worrell, JA, Stahlman, MT, Phillips, JA, Loyd, JE, Cogan, JD, Lawson, WE. Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC. Chest, 137(4), 969-73, 2010

Ryder, AB, Tollefson, SJ, Podsiad, AB, Johnson, JE, Williams, JV. Soluble recombinant human metapneumovirus G protein is immunogenic but not protective. Vaccine, 28(25), 4145-52, 2010

Allen, SS, Evans, W, Carlisle, J, Hajizadeh, R, Nadaf, M, Shepherd, BE, Pride, DT, Johnson, JE, Drake, WP. Superoxide dismutase A antigens derived from molecular analysis of sarcoidosis granulomas elicit systemic Th-1 immune responses. Respir Res, 9, 36, 2008

Johnson, JE, Gonzales, RA, Olson, SJ, Wright, PF, Graham, BS. The histopathology of fatal untreated human respiratory syncytial virus infection. Mod Pathol, 20(1), 108-19, 2007

Cseke, G, Wright, DW, Tollefson, SJ, Johnson, JE, Crowe, JE, Williams, JV. Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats. J Virol, 81(2), 698-707, 2007

Devin, JK, Johnson, JE, Eren, M, Gleaves, LA, Bradham, WS, Bloodworth, JR, Vaughan, DE. Transgenic overexpression of plasminogen activator inhibitor-1 promotes the development of polycystic ovarian changes in female mice. J Mol Endocrinol, 39(1), 9-16, 2007

Wright, PF, Ikizler, MR, Gonzales, RA, Carroll, KN, Johnson, JE, Werkhaven, JA. Growth of respiratory syncytial virus in primary epithelial cells from the human respiratory tract. J Virol, 79(13), 8651-4, 2005

Cheng, Q, Zhao, Y, Lawson, WE, Polosukhin, VV, Johnson, JE, Blackwell, TS, Gailani, D. The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice. Blood, 106(9), 3055-7, 2005

Williams, JV, Tollefson, SJ, Johnson, JE, Crowe, JE. The cotton rat (Sigmodon hispidus) is a permissive small animal model of human metapneumovirus infection, pathogenesis, and protective immunity. J Virol, 79(17), 10944-51, 2005

Frank, DB, Abtahi, A, Yamaguchi, DJ, Manning, S, Shyr, Y, Pozzi, A, Baldwin, HS, Johnson, JE, de Caestecker, MP. Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension. Circ Res, 97(5), 496-504, 2005

Miller, GG, Destarac, L, Zeevi, A, Girnita, A, McCurry, K, Iacono, A, Murray, JJ, Crowe, D, Johnson, JE, Ninan, M, Milstone, AP. Acute humoral rejection of human lung allografts and elevation of C4d in bronchoalveolar lavage fluid. Am J Transplant, 4(8), 1323-30, 2004

Halasa, NB, Barr, FE, Johnson, JE, Edwards, KM. Fatal pulmonary hypertension associated with pertussis in infants: does extracorporeal membrane oxygenation have a role. Pediatrics, 112(6 Pt 1), 1274-8, 2003

Tang, YW, Johnson, JE, Browning, PJ, Cruz-Gervis, RA, Davis, A, Graham, BS, Brigham, KL, Oates, JA, Loyd, JE, Stecenko, AA. Herpesvirus DNA is consistently detected in lungs of patients with idiopathic pulmonary fibrosis. J Clin Microbiol, 41(6), 2633-40, 2003

Schr??der, C, Wu, GS, Price, E, Johnson, JE, Pierson, RN, Azimzadeh, AM. Hyperacute rejection of mouse lung by human blood: characterization of the model and the role of complement. Transplantation, 76(5), 755-60, 2003

Goldstein, RE, Netterville, JL, Burkey, B, Johnson, JE. Implications of follicular neoplasms, atypia, and lesions suspicious for malignancy diagnosed by fine-needle aspiration of thyroid nodules. Ann Surg, 235(5), 656-62; discussion 662-4, 2002

Pietsch, JB, Shankar, S, Ford, C, Johnson, JE. Obstructive jaundice secondary to lymphoma in childhood. J Pediatr Surg, 36(12), 1792-5, 2001

Foster, MR, Johnson, JE, Olson, SJ, Allred, DC. Immunohistochemical analysis of nuclear versus cytoplasmic staining of WT1 in malignant mesotheliomas and primary pulmonary adenocarcinomas. Arch Pathol Lab Med, 125(10), 1316-20, 2001

Lowe, LH, Isuani, BH, Heller, RM, Stein, SM, Johnson, JE, Navarro, OM, Hernanz-Schulman, M. Pediatric renal masses: Wilms tumor and beyond. Radiographics, 20(6), 1585-603, 2000

Fischer, JE, Johnson, JE, Johnson, TR, Graham, BS. Pertussis toxin sensitization alters the pathogenesis of subsequent respiratory syncytial virus infection. J Infect Dis, 182(4), 1029-38, 2000

Aronica, MA, Mora, AL, Mitchell, DB, Finn, PW, Johnson, JE, Sheller, JR, Boothby, MR. Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo. J Immunol, 163(9), 5116-24, 1999

Fisher, RG, Johnson, JE, Dillon, SB, Parker, RA, Graham, BS. Prophylaxis with respiratory syncytial virus F-specific humanized monoclonal antibody delays and moderately suppresses the native antibody response but does not impair immunity to late rechallenge. J Infect Dis, 180(3), 708-13, 1999