.

Department of Pathology, Microbiology, and Immunology

 

 

  Alison L. Woodworth, Ph.D.

 

 

Associate Professor

Dept of Pathology, Microbiology and Immunology

Director, Esoteric Chemistry

Director, Clinical Chemistry Fellowship Program

 

   Contact Information 
 


   Office Location:

4918 EA TVC

Nashville, TN 37232-5310

Phone: 615-322-0905     

E-mail: alison.woodworth@vanderbilt.edu

 

Campus Mail address:

Pathology Labs/Blood Bank

4605 TVC (5310)

US Mailing address:

Pathology Labs/Blood Bank

Vanderbilt University School of Medicine

4605 TVC

Nashville, TN 37232-5310

 

 

Education

 

 

PhD, Washington University, St. Louis
BS, Vanderbilt

 

 

Research Keywords

 

 

Biomarker Assay Development, Sepsis, Maternal/Fetal medicine

 

 

Research Description

 

 


 

 

Clinical Research Description

 

 

Our lab is working to identify biomarkers that predict a number of pregnancy anomolies. First, we are interested in identifying panels of biomarkers that predict preterm birth in pregnant women with symptoms of labor. We hope to taylor diagnostic algorithm to fit specific patient characteristics such as race, pregnancy and clinical history. Other maternal/fetal medicine related projects include: we are (1) discovery of biomarkers that identify early pregnancy loss in infertile women, (2) Characterization of biomerkers to predict ectopic pregnancy, (3) Analysis of the Predictive value of biomarkers to predict pre-eclampsia.
A second area focus is in biomerkers discovery in sepsis. Specifically we investigating the clinical utility of a panel of biomarkers to predict sepsis in a population of ICU patients with systemic inflammation.

 

 

Publications

 

 

O''Keeffe, EK, Rhodes, MM, Woodworth, A. A patient with a previous diagnosis of hemoglobin S/C disease with an unusually severe disease course. Clin Chem, 55(6), 1228-31; discussion 1231-3, 2009

Gronowski, AM, Cervinski, M, Stenman, UH, Woodworth, A, Ashby, L, Scott, MG. False-negative results in point-of-care qualitative human chorionic gonadotropin (hCG) devices due to excess hCGbeta core fragment. Clin Chem, 55(7), 1389-94, 2009

Woodworth, A, Moore, J, G'sell, C, Verdoes, A, Snyder, JA, Morris, L, Wares, C, Grenache, DG, Gronowski, AM. Diagnostic accuracy of cervicovaginal interleukin-6 and interleukin-6:albumin ratio as markers of preterm delivery. Clin Chem, 53(8), 1534-40, 2007

Woodworth, A, Saunders, AN, Koenig, JW, Moyer, TP, Turk, J, Dietzen, DJ. Differentiation of amphetamine/methamphetamine and other cross-immunoreactive sympathomimetic amines in urine samples by serial dilution testing. Clin Chem, 52(4), 743-6, 2006

Woodworth, A, Pesheva, P, Fiete, D, Baenziger, JU. Neuronal-specific synthesis and glycosylation of tenascin-R. J Biol Chem, 279(11), 10413-21, 2004

Woodworth, A, Fiete, D, Baenziger, JU. Spatial and temporal regulation of tenascin-R glycosylation in the cerebellum. J Biol Chem, 277(52), 50941-7, 2002

Woodworth, A, Baenziger, JU. The man/GalNAc-4-SO4-receptor has multiple specificities and functions. Results Probl Cell Differ, 33, 123-38, 2001