.

Department of Pathology, Microbiology, and Immunology

 

   Paisit Paueksakon, M.D.

 

 

Associate Professor

Dept of Pathology, Microbiology and Immunology

Associate Director of Renal Pathology

 

  Contact Information

 

 

Office Location:

Rm. 2318B

Phone:  615-322-1350

Fax:    615-343-7089

E-mail: paisit.paueksakon@vanderbilt.edu

 

Campus Mail address:

Pathology, Microbiology and Immunology - 3rd Fl

MCN C-3321 (2561)

 

US Mailing address:

Vanderbilt University School of Medicine

Dept of Pathology, Microbiology and Immunoogy - 3rd Fl

MCN C-3321

Nashville, TN 37232-2561

 

 

 

Education

 

 

M.D., Phramongkutklao College of Medicine affiliated with Mahidol University, Bangkok, Thailand

 

 

Research Keywords

 

 

Renal amyloidosis, Light chain deposition disease, Diabetic nephropathy, hypertensive nephrosclerosis, CNS vasculitis, and Restless legs syndrome.

 

 

Research Description

 

 

My research focuses are pathogenesis and mechanisms of light chain deposition disease, amyloidosis, diabetic nephropathy, hypertensive nephrosclerosis, restless legs syndrome and CNS vasculitis.

 

 

Clinical Research Description

 

 

Research efforts primarily concern renal pathology involving mechanisms and pathophysiology of diabetic nephropathy and dysprotinemia

 

 

Publications

 

 

Cheng H, Wang H, Fan X, Paueksakon P, Harris RC. Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Kidney Int, July 11, 2012

Wang, H, Chen, X, Su, Y, Paueksakon, P, Hu, W, Zhang, MZ, Harris, RC, Blackwell, TS, Zent, R, Pozzi, A. p47(phox) contributes to albuminuria and kidney fibrosis in mice. Kidney Int, 2015

Novitskaya, T, McDermott, L, Zhang, KX, Chiba, T, Paueksakon, P, Hukriede, NA, de Caestecker, MP. A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury. Am J Physiol Renal Physiol, 306(5), F496-504, 2014

Grove, KJ, Voziyan, PA, Spraggins, JM, Wang, S, Paueksakon, P, Harris, RC, Hudson, BG, Caprioli, RM. Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles. J Lipid Res, 55(7), 1375-1385, 2014

Paueksakon, P. Renal Pathology: SC23-3 HYPERTENSION-ASSOCIATED VASCULAR DISEASE. Pathology, 46 Suppl 2, S40, 2014

Zhang, MZ, Wang, Y, Paueksakon, P, Harris, RC. Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy. Diabetes, 63(6), 2063-72, 2014

Paueksakon, P, Fogo, AB, Sethi, S. Leukocyte chemotactic factor 2 amyloidosis cannot be reliably diagnosed by immunohistochemical staining. Hum Pathol, 45(7), 1445-50, 2014

Paueksakon, P, Fogo, AB, Sethi, S. Leukocyte chemotactic factor 2 amyloidosis cannot be reliably diagnosed by immunohistochemical staining--reply. Hum Pathol, 45(10), 2179-80, 2014

Paueksakon, P, Fogo, AB. More light shed on light chains. Nephrol Dial Transplant, 29(10), 1799-801, 2014

Gangadhariah, MH, Luther, JM, Garcia, V, Paueksakon, P, Zhang, MZ, Hayward, SW, Love, HD, Falck, JR, Manthati, VL, Imig, JD, Schwartzman, ML, Zent, R, Capdevila, JH, Pozzi, A. Hypertension Is a Major Contributor to 20-Hydroxyeicosatetraenoic Acid-Mediated Kidney Injury in Diabetic Nephropathy. J Am Soc Nephrol, 2014

Nzerue, C, Oluwole, K, Adejorin, D, Paueksakon, P, Fremont, R, Akatue, R, Faulkner, M. Malignant hypertension with thrombotic microangiopathy and persistent acute kidney injury (AKI). Clin Kidney J, 7(6), 586-9, 2014

Moiz, A, Javed, T, Garces, J, Staffeld-Coit, C, Paueksakon, P. Late recurrence of light chain deposition disease after kidney transplantation treated with bortezomib: a case report. Ochsner J, 14(3), 445-9, 2014

Kleinfeld, K, Jones, P, Riebau, D, Beck, A, Paueksakon, P, Abel, T, Claassen, DO. Vascular complications of fungal meningitis attributed to injections of contaminated methylprednisolone acetate. JAMA Neurol, 70(9), 1173-6, 2013

Alfaro, R, Vasavada, N, Paueksakon, P, Hernandez, GT, Aronoff, GR. Cocaine-induced acute interstitial nephritis: A case report and review of the literature. J Nephropathol, 2(3), 204-9, 2013

Gewin, L, Vadivelu, S, Neelisetty, S, Srichai, MB, Paueksakon, P, Pozzi, A, Harris, RC, Zent, R. Deleting the TGF-?? receptor attenuates acute proximal tubule injury. J Am Soc Nephrol, 23(12), 2001-11, 2012

Gewin L, Vadivelu S, Neelisetty S, Srichai MB, Paueksakon P, Pozzi A, Harris RC, Zent R. Deleting the TGF-beta receptor attenuates acute proximal tubule injury . J Am Soc Nephrol, 23, 2001-11, 2012

Oluwole K, Esuzar L, Oluwafisaya A, Nzerue C, Faulkner M, Umeukeje E, Paueksakon P. Pulmonary hemorrhage with hematuria: do not forget IgA nephropathy. Clinical Kidney Journal, 5, 463-466, 2012

Dash A., Fatima H, Grewal M, Galphin C, Paueksakon P. Renal injury due to anti-GBM antibody-mediated glomerulonephritis without circulating antibody. Clinical Kidney Journal, 1-4, 2012

Yu, L, Su, Y, Paueksakon, P, Cheng, H, Chen, X, Wang, H, Harris, RC, Zent, R, Pozzi, A. Integrin ??1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy. Kidney Int, 81(11), 1086-97, 2012

Weinstock LB, Walters AS, Paueksakon P. Restless Legs Syndrome: Theoretical Roles of Inflammatory and Immune Mechanism . Sleep Med Rev, 16, 341-54, 2012

Ruangkanchanasetr, P, Praechinavong, W, Paueksakon, P, Satirapoj, B, Supasyndh, O, Supaporn, T. Isometric tubular vacuolization in renal transplant recipient: the first case report in Thailand. J Med Assoc Thai, 95 Suppl 5, S168-71, 2012

Cheng, H, Wang, H, Fan, X, Paueksakon, P, Harris, RC. Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Kidney Int, 82(11), 1176-83, 2012

Yu L, Su Y, Paueksakon P., Cheng H, Harris RC, Zent, R, Pozzi, A.. Integrin alpha 1/Akita double null mice on the Balb/c background develop advanced diabetic nephropathy. Kidney Int, 8, 1086-97, 2012

Weinstock, LB, Walters, AS, Paueksakon, P. Restless legs syndrome--theoretical roles of inflammatory and immune mechanisms. Sleep Med Rev, 16(4), 341-54, 2012

Satirapoj, B, Paueksakon, P. A concurrence of light and heavy chain deposition disease and diabetic nephropathy. J Med Assoc Thai, 90(10), 2204-8, 2007

Nabangchang, C, Sakoolnamarka, S, Paueksakon, P, Chinvarun, Y. Epilepsy surgery in children and adolescence; Phramongkutklao College of Medicine''s experience. J Med Assoc Thai, 88 Suppl 3, S263-70, 2005

Paueksakon P, Blacklock JB, Powell SZ, Goodman JC. A 79 year old woman with right frontal lobe mass; prior history of breast cancer and meningioma. Brain Pathol , 14, 113-5, 2004

Paueksakon, P, Revelo, MP, Horn, RG, Shappell, S, Fogo, AB. Monoclonal gammopathy: significance and possible causality in renal disease. Am J Kidney Dis, 42(1), 87-95, 2003

Paueksakon P, Revelo MP, Horn HG, Shappell SB Fogo AB. Monoclonal gammopathy: significance and causality in renal disease. Am J Kidney Dis, 42, 87-95, 2003

Paueksakon, P, Revelo, MP, Ma, LJ, Marcantoni, C, Fogo, AB. Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy. Kidney Int, 61(6), 2142-8, 2002

Paueksakon, P, Parker, JR, Fan, X, Miles, G, Ruiz, H, Wushensky, C, Johnson, MD. Melanotic neuroectodermal tumor of infancy discovered after head trauma. Pediatr Neurosurg, 36(1), 33-6, 2002

Paueksakon P, Revelo MP, Ma L-J, Marcantoni C, Fogo AB. Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy. Kidney Int , 61, 2142-2148, 2002

Revelo, MP, Paueksakon, P, Goral, S, Helderman, H, Fogo, AB. A 14-year-old boy with kidney allograft failure in the first month after transplantation. Am J Kidney Dis, 36(4), 871-4, 2000