Department of Pathology, Microbiology, and Immunology


Mohamed Mokhtar Desouki, M.D., Ph.D.



Associate Professor

Dept. of Pathology, Microbiology and Immunology



Contact Information



Office Location:
MCN C-2310A

Phone: 615-343-9540
: mohamed.desouki@vanderbilt.edu


Campus Mail address:

Pathology, Microbiology and Immunology-3rd Fl

MCN C-3321 (2561)


US Mailing address:
Vanderbilt University School of Medicine
Dept of Pathology, Microbiology and Immunology-3rd Fl
MCN C-3321

Nashville, TN 37232-2561






MBBCh, Faculty of Medicine, Cairo University, Egypt
Master and Doctorate (PhD), Faculty of Medicine, Cairo University, Egypt
AP Fellowship, MUSC, Charleston, SC, USA
Breast/Gyn Fellowship, UPMC, Pittsburgh, PA, USA
Ap/CP Pathology Residency, MUSC, Charleston, SC, USA



Research Keywords



Cancer Breast, Gynecologic Pathology, Prostate Cancer



Research Description








Weiss, VL, Cate, F, Bloom, L, Fadare, O, Coogan, AC, Desouki, MM. Age cut-off for reporting endometrial cells on a Papanicolaou test: 50 years may be more appropriate than 45 years. Cytopathology, 2015

Ferguson, DC, Long, DJ, Smith, MC, Craig-Owens, LD, Means, J, Fadare, O, Desouki, MM. Comparative analysis of Rb1, P16 and ER as diagnostic, prognostic and potential targets for therapeutic agents in ovarian epithelial tumors: an immunohistochemical study of 130 ovarian carcinomas. J Ovarian Res, 8, 34, 2015

Desouki, MM, Franklin, RB, Costello, LC, Fadare, O. Persistent low expression of hZip1 in mucinous carcinomas of the ovary, colon, stomach and lung. J Ovarian Res, 8, 40, 2015

Chamberlain, BK, Fadare, O, Desouki, MM. The role of immunohistochemistry in the evaluation of gynecologic pathology: a single institutional experience. Ann Diagn Pathol, 19(2), 88-90, 2015

Desouki, MM, Long, DJ. Malignant Mesothelioma Mimicking Invasive Mammary Carcinoma in a Male Breast. Case Rep Oncol Med, 2015, 298523, 2015

Fadare, O, Zhao, C, Khabele, D, Parkash, V, Quick, CM, Gwin, K, Desouki, MM. Comparative analysis of Napsin A, alpha-methylacyl-coenzyme A racemase (AMACR, P504S), and hepatocyte nuclear factor 1 beta as diagnostic markers of ovarian clear cell carcinoma: an immunohistochemical study of 279 ovarian tumours. Pathology, 47(2), 105-11, 2015

Desouki, MM, Khabele, D, Crispens, MA, Fadare, O. Ovarian mucinous tumor with malignant mural nodules: dedifferentiation or collision. Int J Gynecol Pathol, 34(1), 19-24, 2015

Desouki, MM, Chamberlain, BK, Li, Z. The role of immunohistochemistry in the evaluation of gynecologic pathology part 2: a comparative study between two academic institutes. Ann Diagn Pathol, 19(5), 296-300, 2015

Desouki, MM. Reduction mammoplasty is beneficial in women with and without history of breast cancer. Womens Health (Lond Engl), 11(4), 419-22, 2015

Desouki, MM, Fadare, O, Chamberlain, BK, Shakir, N, Kanbour-Shakir, A. Malignancy associated with ovarian teratomas: frequency, histotypes, and diagnostic accuracy of intraoperative consultation. Ann Diagn Pathol, 19(3), 103-6, 2015

Li, Z, Fadare, O, Hameed, O, Zhao, C, Desouki, MM. Incidental atypical proliferative lesions in reduction mammoplasty specimens in patients with a history of breast cancer. Hum Pathol, 45(1), 104-9, 2014

Hameed, O, Wei, S, Desouki, MM, Umphrey, H. Breast Cancer: Advances in Surgical Pathology. Series editor Philip T. Cagle and Timothy C Allen. Publisher: Lippincott Williams & Wilkins. ISBN-10: 1451191715., 2014

Khoury, T, Karabakhtsian, RG, Mattson, D, Yan, L, Syriac, S, Habib, F, Liu, S, Desouki, MM. Pleomorphic lobular carcinoma in??situ of the breast: clinicopathological review of 47 cases. Histopathology, 64(7), 981-93, 2014

Desouki, MM, Fadare, O, Kanbour, A, Kanbour-Shakir, A. Immunophenotype and K-RAS mutation in mucinous ovarian adenocarcinoma with mural nodule of high-grade sarcoma: case report. Int J Gynecol Pathol, 33(2), 186-90, 2014

Mohamed, SA, Atta, IS, Rowan, BG, Desouki, MM. ER?? and ERK1/2 MAP kinase expression in microdissected stromal and epithelial endometrial cells. J Egypt Natl Canc Inst, 26(1), 37-41, 2014

Desouki, MM, Kallas, SJ, Khabele, D, Crispens, MA, Hameed, O, Fadare, O. Differential vimentin expression in ovarian and uterine corpus endometrioid adenocarcinomas: diagnostic utility in distinguishing double primaries from metastatic tumors. Int J Gynecol Pathol, 33(3), 274-81, 2014

Desouki, MM, Doubinskaia, I, Gius, D, Abdulkadir, SA. Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer. Hum Pathol, 45(5), 1071-7, 2014

Fadare, O, Parkash, V, Gwin, K, Hanley, KZ, Jarboe, EA, Liang, SX, Quick, CM, Zheng, W, Rawish, KR, Hecht, JL, Desouki, MM. Utility of ??-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas. Hum Pathol, 44(12), 2814-21, 2013

Desouki, MM, Lioyd, J, Xu, H, Cao, D, Barner, R, Zhao, C. CDX2 may be a useful marker to distinguish primary ovarian carcinoid from gastrointestinal metastatic carcinoids to the ovary. Hum Pathol, 44(11), 2536-41, 2013

Fadare, O, Liang, SX, Crispens, MA, Jones, HW, Khabele, D, Gwin, K, Zheng, W, Mohammed, K, Parkash, V, Hecht, JL, Desouki, MM. Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance. Hum Pathol, 44(8), 1508-15, 2013

Desouki, MM, Li, Z, Hameed, O, Fadare, O, Zhao, C. Incidental atypical proliferative lesions in reduction mammoplasty specimens: analysis of 2498 cases from 2 tertiary women''s health centers. Hum Pathol, 2013

Gonzalez, RS, Chamberlain, BK, Giannico, G, Fadare, O, Crispens, MA, Khabele, D, Desouki, MM . Ovarian Serous Borderline Tumor Identified in Endometrial Biopsy: A Case Report.. Gynecology & Obstetrics, 179(3:), 2013

Li, X, Weaver, O, Desouki, MM, Dabbs, D, Shyum, S, Carter, G, Zhao, C. Microcalcification is an important factor in the management of breast intraductal papillomas diagnosed on core biopsy. Am J Clin Pathol, 138(6), 789-95, 2012

Zhao, C, Desouki, MM, Florea, A, Mohammed, K, Li, X, Dabbs, D. Pathologic findings of follow-up surgical excision for lobular neoplasia on breast core biopsy performed for calcification. Am J Clin Pathol, 138(1), 72-8, 2012

Desouki, MM, Liao, S, Conroy, J, Nowak, NJ, Shepherd, L, Gaile, DP, Geradts, J. The genomic relationship between primary breast carcinomas and their nodal metastases. Cancer Invest, 29(4), 300-7, 2011

Desouki, MM, Liao, S, Huang, H, Conroy, J, Nowak, NJ, Shepherd, L, Gaile, DP, Geradts, J. Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach. J Cancer Res Clin Oncol, 137(5), 795-809, 2011

Desouki, MM, Post, GR, Cherry, D, Lazarchick, J. PAX-5: a valuable immunohistochemical marker in the differential diagnosis of lymphoid neoplasms. Clin Med Res, 8(2), 84-8, 2010

Desouki, MM, Kulawiec, M, Bansal, S, Das, GM, Singh, KK. Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors. Cancer Biol Ther, 4(12), 1367-73, 2005

Desouki, MM, Rowan, BG. SRC kinase and mitogen-activated protein kinases in the progression from normal to malignant endometrium. Clin Cancer Res, 10(2), 546-55, 2004