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HoxB7-Cre - Renal specific transgenic database

Common name HoxB7-Cre
Mouse strain Outbred
Genebank listing: HOXB7 (15415)
Source Andrew McMahon (email)
Renal cell types Principal cells (collecting duct),Intercalated cells Type A (collecting duct),Intercalated cells Type B (collecting duct),Intercalated cells Type non-A/N (collecting duct),Ureteric bud,Ureteric bud tip,Ureteric bud stalk
Extent of expression/recombination in renal target cells Collecting duct from inner medulla to cortical collecting duct
Other cell types throughout ureteric bud-derived epithelium
Applications collecting duct gene targeting in the kidney (does not include CNT)
Image (click to zoom) None provided
  • Rubera I, Loffing J, Palmer LG, Frindt G, Fowler-Jaeger N, Sauter D, Carroll T, McMahon A, Hummler E, Rossier BC. Collecting duct-specific gene inactivation of alphaENaC in the mouse kidney does not impair sodium and potassium balance. J Clin Invest (2003) 112:554-65 View in PubMed

  • Yu J, Carroll TJ, McMahon AP. Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development (2002) 129:5301-12 View in PubMed

Availability Yes
Available states
Available at (source) Jackson Labs. Strain ID: 004692
Added on/by 2010-01-19 / Donald Kohan
Modified on/by 2010-03-01 / Donald Kohan